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Is the “Ideal” γ-Probe for Intraoperative Radioguided Surgery Conceivable?

Is the “Ideal” γ-Probe for Intraoperative Radioguided Surgery Conceivable?

Publication in this issue of The Journal of Nuclear Medicine of the article by Classe et al. (pages 395–399 (1)) gives the opportunity for some considerations both from a speculative and from a practical point of view about the use of intraoperative γ-probes for radioguided surgery.
  • Giuliano Mariani, Angela Vaiano, Otello Nibale and Domenico Rubello
  • Journal of Nuclear Medicine March 2005, 46 (3) 388-390;

REFERENCES 1. Classe J-M, Fiche M, Rousseau C, et al. Prospective comparison of 3-probes for sentinel lymph node detection in 200 breast cancer patients. J Nucl Med. 2005;46:395–399. 2. Kwo DP, Barber HB, Barrett HH, Hickernell TS, Woolfenden JM. Comparison of NaI(Tl), CdTe, In: Early BS, Sodee DB, O’Donnell JK, eds. Principles and Practice of Nuclear Medicine. 2nd ed. Philadelphia, PA: W.B. Saunders; 1995:292–297. 4. Tiourina T, Arends B, Huysmans D, Rutten H, Lemaire B, Muller S. Evaluation of surgical gamma probes for radioguided sentinel node localization. Eur J Nucl Med. 1998;25:1224–1231. 5. Britten A. A method to evaluate intra-operative gamma probes for sentinel lymph node localization. Eur J Nucl Med. 1999;26:76–83. 6. Schneebaum S, Even-Sapir E, Cohen M, et al. Clinical applications of gamma-detection probes: radioguided surgery. Eur J Nucl Med. 1999; 26(suppl):S26–S35. 7. Chiesa C, Toscano F, Maffioli L, Bombardieri E. Intra-operative probes: constancy of performances [abstract]. Eur J Nucl Med. 2000;27:989. 8. Zanzonico P, Heller S. The intraoperative gamma probe: basic principles and choices available. Semin Nucl Med. 2000;30:33–48. 9. Chiesa C, Toscano F, Mariani M, Bombardieri E. Intraoperative gamma probes: systematic intercomparison of 17 commercial devices under identical experimental conditions—introduction of a simple physical figure of merit [abstract]. Eur J Nucl Med. 2001;28:1110. 10. Mariani G, Moresco L, Villa G, et al. Radioguided sentinel lymph node biopsy in breast cancer surgery. J Nucl Med. 2001;42:1198–1215. and HgI2 surgical probes: effect of scatter compensation on probe performance. Med Physics. 1991; 18:382–389. 3. Woolfenden JM, Barber HB. Intraoperative probes. 390 11. Mariani G, Gipponi M, Moresco L, et al. Radioguided sentinel lymph node biopsy in malignant cutaneous melanoma. J Nucl Med. 2002;43:811827. 12. Mariani G, Gulec SA, Rubello D, et al. Preoperative localization and radioguided parathyroid surgery. J Nucl Med. 2003;44:1443–1458. 13. Wengenmair H, Kopp J, Sciuk J. Quality criteria of gamma probes: requirements and future developments. In: Schauer AJ, Becker W, Reiser M, Possinger K, eds. The Sentinel Lymph Node Concept. New York, NY: Springer; 2005:113–125.

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